Homeopathy showed greater efficacy in MDD compared with fluoxetine, and in premenstrual syndrome/dysphoric disorder compared with placebo, whereas no difference emerged between homeopathy and placebo in MDD and attention deficit/hyperactivity disorder.Īvailable data on homeopathy in psychiatric disorders are insufficient to support their use in clinical practice. Eight of 9 randomized controlled trials showed high risk of bias. All randomized controlled trials enrolling patients with any psychiatric disorder and comparing HR with placebo, no treatment, or other psychotropic drugs were included.Ī total of 212 studies were screened, 9 met all selection criteria and reported data on major depressive disorder (MDD) (n = 4), generalized anxiety disorder (n = 1), attention-deficit/hyperactivity disorder (n = 2), and premenstrual syndrome/dysphoric disorder (n = 2). We performed a Medline/Embase search for studies written in English and published from any date to October 23, 2018. The aim is to assess the efficacy of HRs in the treatment of mental disorders. Nonetheless, homeopathic remedies (HRs) are widespread throughout the world and especially in mental disorders. Conclusive evidence on the plausibility, efficacy, and safety of these treatments is not currently available. Homeopathy is a complementary and alternative medicine. Some steps have been suggested to overcome these challenges, namely improving research education among homoeopathic fraternity, ensuring precise application of principles of homoeopathy as well as utilising correct research methodology, promoting interdisciplinary communication and encouraging interaction between academicians, researchers and practitioners and taking steps to improve the quality of documentation. (3) difficulties arising due to logistic challenges-lack of well-trained homoeopathic physicians in principles of homoeopathy as well as research, lack of proper infrastructure leading to hurdles such as limited access to research literature and other necessary resources (4) research culture-these pertain to the difficulties in homoeopathic research stemming from the reluctance of the homoeopathic society to assimilate research into its culture. We have classified and compiled the challenges broadly under the headings of (1) conceptual challenges-difficulties in research arising due to conceptual differences between homoeopathy and conventional medicine, in the understanding of disease and its treatment (2) methodological challenges-such as weak study designs, use of incorrect outcome measures, lack of knowledge of statistics, poor adherence to homoeopathic tenets leading to poor remedy selection etc. Through this article, we attempt to identify and understand some of the major challenges in homoeopathic research and find solutions to overcome them. En la presente revisión de la literatura disponible, se describen de una forma crítica y rigurosa, los principios de la homeopatía, las evidencias experimentales de su funcionamiento, y su idoneidad en la medicina actual, para determinar si puede considerarse una práctica médica y veterinaria aceptable en el siglo XXI. La debilidad del marco teórico de la homeopatía y la escasa evidencia seria que ha proporcionado dificulta su consideración como una herramienta de la medicina científica moderna. Conceptos aplicados en la homeopatía como el de similia similibus curentur, fuerza vital, dinamización, dosis mínimas o infinitesimales, y otras peculiaridades de la práctica, son poco reconocidos en la actualidad o incluso rechazados por completo. Desde sus inicios y hasta la época moderna, los postulados de la homeopatía han sido motivo de debates en la medicina y en la ciencia. Su origen se remonta a poco más de 200 años y su popularidad ha tenido altibajos desde entonces. La homeopatía es una de las prácticas más utilizadas en la medicina alternativa, tanto en la atención de pacientes humanos como en veterinaria.
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